Other Names EC 2.7.10.1, HGF receptor, HGF-SF receptor, Hepatocyte growth factor receptor precursor, Met proto- oncogene tyrosine kinase, c-met, kinase EC 2.7.10.1, HGF receptor, HGF-SF receptor, Hepatocyte growth factor receptor precursor, Met proto- oncogene tyrosine kinase, c-met, kinase Met
All Sites Human: Tyr1003; Mouse: Tyr1001; Rat: Tyr1004
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human c-Met around the phosphorylation site of tyrosine 1003 (V-D-YP-R-A).
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity c-Met (Phospho-Tyr1003) antibody detects endogenous levels of c-Met only when phosphorylated at tyrosine 1003.
ReferencesMasahide Tokunou, Am. J. Pathol., Apr 2001; 158: 1451.
Jolanta Chmielowiec, J. Cell Biol., Apr 2007; 177: 151 - 162.
Yunqing Li, Cancer Res., Oct 2005; 65: 9355 - 9362.
Mario Beilmann, Blood, Dec 1997; 90: 4450 - 4458.
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells