Other Names CENA, CENP-A, CENPA, Centromere autoantigen A, Centromere protein A
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human Centromeric Protein A around the phosphorylation site of serine 7 (R-R-SP-R-K).
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity Centromeric Protein A (Phospho-Ser7) antibody detects endogenous levels of Centromeric Protein A only when phosphorylated at serine 7.
ReferencesBlack B.E., Nature 430:578-582(2004).
Olsen J.V., Cell 127:635-648(2006).
Foltz D.R., Nat. Cell Biol. 8:458-469(2006).
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Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells