Other Names 39 kDa protein kinase, CAK, CAK1, CDK-activating kinase, CDKN7, CR4 protein kinase, CRK4, Cell division protein kinase 7, EC 2.7.11.22, EC 2.7.11.23, MO15, MPK-7, P39 Mo15, Protein-tyrosine kinase MPK-7, STK1, TFIIH basal complex kinase subunit, kinase Cdk7
All Sites Human: Thr170; Mouse: Thr170
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human CDK7 around the phosphorylation site of threonine 170(A-Y-TP-H-Q).
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity CDK7 (Phospho-Thr170) antibody detects endogenous levels of CDK7 only when phosphorylated at threonine 170.
ReferencesJ. Matt Kim, Biol Reprod, May 2001; 64: 1400.
Ann Yee, Cancer Res., Dec 1995; 55: 6058 - 6062.
Saya Ito. Genes Cells, Oct 2004; 9: 983 - 992.
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells