Other Names C5AR, C5AR1, C5R1, C5a anaphylatoxin chemotactic receptor, C5a-R, CD88 antigen
All Sites Human: Ser338; Mouse: Ser335
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human CD88/C5aR around the phosphorylation site of serine 338 (T-R-SP-T-V).
Purification The antibody was affinity-purified fromrabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity CD88/C5aR (Phospho-Ser338) antibody detects endogenous levels of CD88/C5aR only when phosphorylated at serine 338.
ReferencesGerard N.P., Nature 349:614-617(1991).
Boulay F., Biochemistry 30:2993-2999(1991).
Gerard N.P., Biochemistry 32:1243-1250(1993).
Farzan M., J. Exp. Med. 193:1059-1066(2001).
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells