Other Names EC 3.1.3.48, L-CA, LY-5, Leukocyte common antigen precursor, Leukocyte common antigen variant 4 precursor, Lymphocyte common antigen Ly-5, PTPRC, T200
All Sites Human: Ser1007; Mouse: Ser996; Rat: Ser960
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human CD45 around the phosphorylation site of serine 1007 (D-D-SP-D-S).
Purification The antibody was affinity-purified fromrabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity CD45 (Phospho-Ser1007) antibody detects endogenous levels of CD45 only when phosphorylated at serine 1007.
ReferencesStreuli M., O J. 9:2399-2407(1990).
Wu L., Mol. Cell. Biol. 22:2673-2686(2002).
Beausoleil S.A., Proc. Natl. Acad. Sci. U.S.A. 101:12130-12135(2004).