Other Names CD4, T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4 precursor
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human CD4 around the phosphorylation site of serine 433 (R-M-SP-Q-I).
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity CD4 (Phospho-Ser433) antibody detects endogenous levels of CD4 only when phosphorylated at serine 433.
ReferencesGR Harriman, J. Immunol., Oct 1990; 145: 2406.
G Zauli, Blood, Sep 1994; 84: 1896 - 1905.
Andrew Zloza, Blood, Sep 2003; 102: 2156 - 2164.
David M. Rothstein, Int. Immunol., Jan 1993; 5: 409 - 418.
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells