Other Names CD18; cell surface adhesion glycoproteins LFA- 1/CR3/p150,95 beta; complement receptor C3 beta; integrin beta-2; ITB2
All Sites Human: Thr758; Mouse: Thr760; Rat: Thr757
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human CD18/ITGB2 around the phosphorylation site of threonine 758 (S-A-TP-T-T).
Purification The antibody was affinity-purified fromrabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity CD18/ITGB2 (Phospho-Thr758) antibody detects endogenous levels of CD18/ITGB2 only when phosphorylated at threonine 578.
ReferencesKishimoto T.K., Cell 48:681-690(1987).
Weitzman J.B., FEBS Lett. 294-97-103(1991).
Hattori M., Nature 405:311-319(2000).
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells