Other Names CAM kinase I, CAMK1, Calcium/calmodulin-dependent protein kinase type I, EC 2.7.11.17, KCC1, KCC1A, kinase CaMK1-alpha
All Sites Human: Thr177; Mouse: Thr177; Rat: Thr177
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human CaMK1-α around the phosphorylation site of threonine 177 (L-S-TP-A-C).
Purification The antibody was affinity-purified fromrabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity CaMK1-α (Phospho-Thr177) antibody detects endogenous levels of CaMK1-α only when phosphorylated at threonine 177.
ReferencesHaribabu B., EMBO J. 14:3679-3686(1995).
Gevaert K., Nat. Biotechnol. 21:566-569(2003).
Hsu L.-S., J. Biol. Chem. 276:31113-31123(2001).
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells