Other Names BAD, BBC6, BCL2L8, Bcl- XL/Bcl-2 associated death promoter, Bcl-2 binding component 6, Bcl-2-like 8 protein, Bcl-xL/Bcl-2 associated death promoter, Bcl2-antagonist of cell death
All Sites Human: Ser91; Mouse: Ser128; Rat: Ser129
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human BAD around the phosphorylation site of serine 91/ serine 128 (E-L-SP-P-F).
Purification The antibody was affinity-purified fromrabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity BAD (Phospho-Ser91/128) antibody detects endogenous levels of BAD only when phosphorylated at serine 91/ serine 128.
ReferencesWang H.-G., Cell 87:629-638(1996).
Ottilie S., J. Biol. Chem. 272:30866-30872(1997).
The MGC Project Team, Genome Res. 14:2121-2127(2004).
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells