Other Names EC 2.7.11.13, KPCZ, PKC-zeta, PKC2, PRKCZ, Protein kinase C zeta type, kinase PKC-zeta, nPKC-zeta
All Sites Human: Thr560; Mouse: Thr560; Rat: Thr560
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human PKC ζ around the phosphorylation site of threonine 560 (Q-L-TP-P-D).
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity PKC ζ (Phospho-Thr560) antibody detects endogenous levels of PKC ζ only when phosphorylated at threonine 560.
ReferencesRichard Magid, Circ. Res., Sep 2005; 97: 443 - 449.
M Fujihara, J. Immunol., Feb 1994; 152: 1898.
A. Banan, Am J Physiol Gastrointest Liver Physiol, May 2002; 282: 794.
A. Banan, Am J Physiol Gastrointest Liver Physiol, Oct 2002; 283: 909.
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells