Other Names Apoptosis regulator Bcl-X, BCL2L, BCL2L1, BCLX, BLC2L, Bcl-2-like 1 protein
All Sites Human: Thr47; Mouse: Thr47; Rat: Thr47
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human BCL-XL around the phosphorylation site of threonine 47 (M-E-TP-P-S).
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against
non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity BCL-XL (Phospho-Thr47) antibody detects endogenous levels of BCL-XL only when phosphorylated at threonine 47.
ReferencesKE Foreman, Am. J. Pathol., Sep 1996; 149: 795.
Mariola Kurowska, J. Immunol., Aug 2002; 169: 1760.
Yun Dai, Mol. Pharmacol., Dec 2003; 64: 1402.
Charles Perkins, Blood, Feb 2000; 95: 1014 - 1022.
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells