Other Names Apoptosis regulator BAX, membrane isoform alpha, BAXA, Bcl2-associated X protein
All Sites Human: Thr167; Mouse: Thr167; Rat: Thr167
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human Bax around the phosphorylation site of threonine 167 (F-G-TP-P-T).
Purification The antibody was affinity-purified fromrabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity Bax (Phospho-Thr167) antibody detects endogenous levels of Bax only when phosphorylated at threonine 167.
ReferencesFrancesca Andriani. J Natl Cancer Inst, Sep 2001; 93: 1314 - 1324.
H Martinez-Valdez. J. Exp. Med., Mar 1996; 183: 971.
Joslyn K. Brunelle. J. Biol. Chem., Feb 2004; 279: 4305 - 4312.
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells