Other Names ADH water channel, AQP-CD, Aquaporin-CD, Collecting duct water channel protein, WCH-CD, Water channel protein for renal collecting duct, aquaporin 2
All Sites Human: Ser256; Mouse: Ser256; Rat: Ser256
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human Aquaporin 2 around the phosphorylation site of serine 256 (R-Q-SP-V-E).
Purification The antibody was affinity-purified fromrabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity Aquaporin 2 (Phospho-Ser256) antibody detects endogenous levels of Aquaporin 2 only when phosphorylated at serine 256.
ReferencesTakeaki Inoue, Am J Physiol Renal Physiol, Nov 1998; 275: 752.
PM Deen, J. Am. Soc. Nephrol., Oct 1997; 8: 1493.
Baoxue Yang, J. Biol. Chem., Jan 2001; 276: 2775 - 2779.
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells