Other Names Angiopoietin 1 receptor precursor, CD202b antigen, EC 2.7.10.1, HYK, P140 TEK, TEK, TIE-2, Tunica interna endothelial cell kinase, Tyrosine-protein kinase receptor TEK, Tyrosine-protein kinase receptor TIE-2, kinase TIE2
All Sites Human: Tyr1102; Mouse: Tyr1100
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human TIE2 around the phosphorylation site of tyrosine 1102 (K-T-YP-V-N).
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity TIE2 (Phospho-Tyr1102) antibody detects endogenous levels of TIE2 only when phosphorylated at tyrosine 1102.
ReferencesMonica Iurlaro, J. Cell Sci., Sep 2003; 116: 3635.
Ok-Hee Lee, Mol. Cancer Res., Dec 2006; 4: 915 - 926.
Bernhard Witzenbichler, J. Biol. Chem., Jul 1998; 273: 18514.
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells