Other Names Choline phosphatase 1, EC 3.1.4.4, Phosphatidylcholine-hydrolyzing phospholipase D1, Phospholipase D1
All Sites Human: Ser561; Mouse: Ser561; Rat: Ser561
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human PLD1 around the phosphorylation site of serine 561 (K-F-SP-L-Y).
Purification The antibody was affinity-purified fromrabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity PLD1 (Phospho-Ser561) antibody detects endogenous levels of PLD1 only when phosphorylated at serine 561.
ReferencesNicholas Lehman, Blood, Nov 2006; 108: 3564 - 3572.
Yoe-Sik Bae, J. Immunol., Apr 2000; 164: 4089.
Maria Zeniou-Meyer, J. Biol. Chem., Jul 2007; 282: 21746 - 21757.
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells