Other Names EC 2.7.11.13, KPCD1, PKC-mu, PKCM, PKD, PRKCM, PRKD1, Protein kinase C, mu type, Protein kinase D, kinase PKD1, nPKC-mu
All Sites Human: Ser910; Mouse: Ser916; Rat: Ser647
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human PKD1/PKC μ around the phosphorylation site of serine 910 (R-V-SP-I-L).
Purification The antibody was affinity-purified fromrabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity PKD1/PKC μ (Phospho-Ser910) antibody detects endogenous levels of PKD1/PKC μ only when phosphorylated at serine 910.
ReferencesJohannes F.-J., J. Biol. Chem. 269:6140-6148(1994).
Zemlickova E., Biochem. Biophys. Res. Commun. 307:459-465(2003).
Sjoeblom T., Science 314:268-274(2006).
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells