Other Names EC 2.7.11.13, KPCD, PKC-delta, PRKCD, kinase PKC-delta, nPKC-delta
All Sites Human: Thr505; Mouse: Thr505; Rat: Thr505
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human PKC δ around the phosphorylation site of threonine 505 (R-A-SP-T-F).
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody againstnon-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity PKC δ (Phospho-Thr505) antibody detects endogenous levels of PKC δ only when phosphorylated at threonine 505.
ReferencesJ. J. Peluso, Endocrinology, Oct 2001; 142: 4203.
Peter Hampson, Blood, Aug 2005; 106: 1362 - 1368.
Peter Hampson, AACR Meeting Abstracts, Apr 2005; 2005: 1262.
Mohammad Asghar, Am J Physiol Renal Physiol, Dec 2003; 285: 1100.
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells