Other Names EC 2.7.11.1, MST-1, Mammalian STE20-like protein kinase 1, STE20-like kinase MST1, STK4, Serine/threonine protein kinase 4, Serine/threonine protein kinase Krs-2, kinase MST1, serine/threonine kinase 4; STE20-like kinase MST1; Yeast Sps1/Ste20-related kinase 3
All Sites Human: Thr183; Mouse: Thr183
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human Mst1/2 around the phosphorylation site of threonine 183(R-N-TP-V-I).
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity Mst1/2 (Phospho-Thr183) antibody detects endogenous levels of Mst1/2 only when phosphorylated at threonine 183.
ReferencesCreasy C.L., J. Biol. Chem. 270:21695-21700(1995).
Deloukas P., Nature 414:865-871(2001).
Cheung W.L., Cell 113:507-517(2003).
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells