Other Names Dual specificity mitogen-activated protein kinase kinase 1, EC 2.7.12.2, ERK activator kinase 1, MAP kinase kinase 1, MAP2K1, MAPK/ERK kinase 1, MAPKK 1, MAPKK1, MEK1, MP2K1, PRKMK1, kinase MEK1
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from humanMEK1 around the phosphorylation site of serine 298 (P-L-SP-S-Y).
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificty Sensitivity
Specificity/Sensitivity MEK1 (Ab-298) antibody detects endogenous levels of total MEK1 protein.
ReferencesSeger R., J. Biol. Chem. 267:25628-25631(1992).
Zheng C.-F., J. Biol. Chem. 268:11435-11439(1993).
Zheng C.-F., EMBO J. 13:1123-1131(1994).
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells