Other Names DBCN, DCX, Doublin, LISX, Lis-X, Lissencephalin-X
All Sites Human: Thr189; Mouse: Thr189
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human LKB1 around the phosphorylation site of throsine 189 (G-G-TP-L-K).
Purification The antibody was affinity-purified fromrabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity LKB1 (Phospho-Thr189) antibody detects endogenous levels of LKB1 only when phosphorylated at throsine 189.
ReferencesNezu J.; Nat. Genet. 18:38-43(1998). Bignell G.R., Cancer Res. 58:1384-1386(1998).
Scanlan M.J., Int. J. Cancer 83:456-464(1999).
Baas A.F., EMBO J. 22:3062-3072(2003).