Other Names EC 2.7.11.1; kinase LKB1; PJS; Serine/threonine kinase KPM; Serine/threonine protein kinase 11; STK11
All Sites Human: Ser428; Mouse: Ser428
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human LKB1 around the phosphorylation site of serine 428 (R-L-SP-A-C).
Purification The antibody was affinity-purified fromrabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity LKB1 (Phospho-Ser428) antibody detects endogenous levels of LKB1 only when phosphorylated at serine 428.
ReferencesJenne D.E., Nat. Genet. 18:38-43(1998).
Bignell G.R., Cancer Res. 58:1384-1386(1998).
Baas A.F., EMBO J. 22:3062-3072(2003).