Other Names 36 kDa phospho-tyrosine adaptor protein; Linker for activation of T cells; p36-38; pp36
All Sites Human: Tyr171; Mouse: Tyr171
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human LAT around the phosphorylation site of tyrosine 171 (D-D-YP-V-N).
Purification The antibody was affinity-purified fromrabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity LAT (Phospho-Tyr171) antibody detects endogenous levels of LAT only when phosphorylated at tyrosine 171
ReferencesM Nicosia, J. Virol., Dec 1993; 67: 7276 - 7283.
Marta Pineda, J. Biol. Chem., Jul 1999; 274: 19738.
Shin-ichiroh Saitoh, J. Exp. Med., Sep 2003; 198: 831.