Other Names ALK tyrosine kinase receptor precursor, Anaplastic lymphoma kinase, CD246, EC 2.7.10.1, kinase ALK
All Sites Human: Tyr1507; Mouse: Tyr1507
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human ALK around the phosphorylation site of tyrosine 1507(P-T-YP-G-S).
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity ALK (Phospho-Tyr1507) antibody detects endogenous levels of ALK only when phosphorylated at tyrosine 1507.
ReferencesMorris S.W., Oncogene 14:2175-2188(1997).
Iwahara T., Oncogene 14:439-449(1997).
Hillier L.W., Nature 434:724-731(2005).
----------------------------------------------------------------------------
------------------------------------------------------------------------------------