Other Names API3, BIR4, BIRC4, Baculoviral IAP repeat-containing protein 4, HILP, IAP-like protein, IAP3, Inhibitor of apoptosis protein 3, X-linked IAP, X-linked inhibitor of apoptosis protein
All Sites Human: Ser87; Mouse: Ser87; Rat: Ser87
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human XIAP around the phosphorylation site of serine 87 (K-V-SP-P-N).
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity XIAP (Phospho-Ser87) antibody detects endogenous levels of XIAP only when phosphorylated at serine 87.
ReferencesAndrew T. Ho, Mol. Cell. Biol., Aug 2007; 27: 5673 - 5685.
Do-Sun Byun, Cancer Res., Nov 2003; 63: 7068 - 7075.
Hamid Kashkar, J. Exp. Med., Jul 2003; 198: 341.
Arnon P. Kater, Blood, Sep 2005; 106: 1742 - 1748.