Other Names EC 2.7.10.1, FLK1, KDR, VGFR2, VGR2, kinase insert domain receptor, protein-tyrosine kinase receptor Flk-1, vascular endothelial growth factor receptor 2
All Sites Human: Tyr1059; Mouse: Tyr1057; Rat: Tyr1055
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human VEGFR2 around the phosphorylation site of tyrosine 1059(P-D-YP-V-R).
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity VEGFR2 (Phospho-Tyr1059) antibody detects endogenous levels of VEGFR2 only when phosphorylated at tyrosine 1059.
ReferencesTerman B.I., Oncogene 6:1677-1683(1991).
Patterson C., J. Biol. Chem. 270:23111-23118(1995).
Mitola S., J. Virol. 74:344-353(2000).