Other Names EC 1.14.16.2, TH isoform 3, TH isoform a, TH-4, TY3H, TYH, Tyrosine 3-hydroxylase, Tyrosine 3-monooxygenase, tyrosine hydroxylase
All Sites Mouse: Ser8; Rat: Ser8
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human Tyrosine Hydroxylase around the phosphorylation site of serine 8 (A-P-SP-P-Q).
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity Tyrosine Hydroxylase (Phospho-Ser8) antibody detects endogenous levels of Tyrosine Hydroxylase only when phosphorylated at serine 8.
ReferencesMarco Cosentino, Blood, Jan 2007; 109: 632 - 642.
ZG Xue, J. Neurosci., Mar 1988; 8: 806.
L Iacovitti, J. Neurosci., Apr 1987; 7: 1264.
DM Kuhn, J. Biol. Chem., Apr 1990; 265: 5780 - 5786.
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells