Other Names Chromosome segregation protein SmcB, DXS423E, KIAA0178, SB1.8/DXS423E protein, SM1A, SMC1A, SMC1L1, SMC1alpha protein, Sb1.8, Structural maintenance of chromosome 1-like 1 protein
All Sites Human: Ser966; Mouse: Ser966
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human SMC1 around the phosphorylation site of serine 966 (S-G-SP-Q-R).
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity SMC1 (Phospho-Ser966) antibody detects endogenous levels of SMC1 only when phosphorylated at serine 966.
ReferencesRocques P.J., Hum. Mol. Genet. 4:243-249(1995).
Nagase T., DNA Res. 3:17-24(1996).
Nakajima D., DNA Res. 9:99-106(2002).
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells