Other Names NR3C3, PGR, PRGR, Progesterone receptor
All Sites Human: Ser294; Mouse: Ser294
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human PR around the phosphorylation site of serine 294 (G-R-SP-P-L).
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity PR (Phospho-Ser294) antibody detects endogenous levels of PR only when phosphorylated at serine 294.
ReferencesKastner P., EMBO J. 9:1603-1614(1990).
Knotts T.A., J. Biol. Chem. 276:8475-8483(2001).
Hsiao P.W., Mol. Cell. Biol. 23:6210-6220(2003).