Other Names CD31, CD31 antigen, EndoCAM, PEC1, PECA1, PECAM, PECAM1, Platelet endothelial cell adhesion molecule precursor
All Sites Human: Tyr713; Mouse: Tyr702
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human PECAM-1 around the phosphorylation site of tyrosine 713 (TET-V-YP-S-EVRKAC).
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity PECAM-1 (Phospho-Tyr713) antibody detects endogenous levels of PECAM-1 only when phosphorylated at tyrosine 713.
ReferencesSimmons D.L., J. Exp. Med. 171:2147-2152(1990).
Famiglietti J., J. Cell Biol. 138:1425-1435(1997).
Wang Y., Am. J. Physiol. 284:H1008-H1017(2003).
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