Other Names Astrocytic phosphoprotein PEA-15, PE15, PEA15, PED, Phosphoprotein enriched in diabetes
All Sites Human: Ser116; Mouse: Ser116; Rat: Ser116
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human PEA-15 around the phosphorylation site of serine 116 (Q-P-SP-E-E).
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity PEA-15 (Phospho-Ser116) antibody detects endogenous levels of PEA-15 only when phosphorylated at serine 116.
ReferencesJoseph Krueger, Mol. Biol. Cell, Aug 2005; 16: 3552 - 3561.
Alessandra Trencia, Mol. Cell. Biol., Jul 2003; 23: 4511 - 4521.
Daniel Kitsberg, J. Neurosci., Oct 1999; 19: 8244.
Angela Glading, Cancer Res., Feb 2007; 67: 1536 - 1544.