Other Names EC 6.3.2.-, PARK2, PRKN, PRKN2, Parkinson disease protein 2, Parkinson juvenile disease protein 2, ubiquitin E3 ligase PRKN
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from human PARKIN around the phosphorylation site of serine 131 (K-D-SP-P-P).
Purification The antibody was affinity-purified fromrabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificty Sensitivity
Specificity/Sensitivity Parkin (Ab-131) antibody detects endogenous levels of total PARKIN protein.
ReferencesJ. Menéndez, Hum. Mol. Genet., Jul 2006; 15: 2045 - 2058.
Miratul M.K. Muqit, Hum. Mol. Genet., Jan 2004; 13: 117 - 135.
Kenny K. K. Chung, Sci. Aging Knowl. Environ., Apr 2004; 2004: or11.
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells