Other Names MITF M1, Microphthalmia-associated transcription factor
All Sites Human: Ser180; Mouse: Ser180
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human MITF around the phosphorylation site of serine 73 (P-N-SP-P-M).
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity MITF (Phospho-Ser180/73) antibody detects endogenous levels of MITF only when phosphorylated at serine 73.
ReferencesJón H. Hallsson, Genetics, May 2004; 167: 233 - 241.
Eiichi Morii, Blood, Apr 2001; 97: 2038 - 2044.
Eiichi Morii, Blood, Sep 2004; 104: 1656 - 1661.
Fatima Lekmine, AACR Meeting Abstracts, Apr 2005; 2005: 394.
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells