Other Names CD117, EC 2.7.10.1, Mast/stem cell growth factor receptor precursor, SCFR, SL, c-kit, kinase Kit
All Sites Human: Tyr703; Mouse: Tyr702
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human KIT around the phosphorylation site of tyrosine 703 (A-L-YP-K-N).
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity KIT (Phospho-Tyr703) antibody detects endogenous levels of KIT only when phosphorylated at tyrosine 703.
ReferencesLiu T., J. Proteome Res. 4:2070-2080(2005).
Syrris P., m. J. Med. Genet. 95:79-81(2000)..
Bignell G., Genes Chromosomes Cancer 45:42-46(2006).
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells