Other Names EC 2.7.10.2, JAK-2, JAK2, Janus kinase 2, kinase Jak2
All Sites Human: Tyr750; Mouse: Tyr750; Rat: Tyr750
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human JAK2 around the phosphorylation site of tyrosine 750 (G-D-YP-G-Q).
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity JAK2 (Phospho-Tyr570) antibody detects endogenous levels of JAK2 only when phosphorylated at tyrosine 750.
ReferencesSaltzman A., Biochem. Biophys. Res. Commun. 246:627-633(1998).
Dalal I., Blood 91:844-851(1998).
Peeters P., Blood 90:2535-2540(1997).
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells