Other Names IL1RAK; IRAK; IRAK-1; Interleukin-1 receptor-associated kinase 1; Pelle-like protein kinase; kinase IRAK1; mPLK
All Sites Human: Thr387; Mouse: Thr387; Rat: Thr387
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human IRAK1 around the phosphorylation site of threonine 387 (R-G-TP-L-A).
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity IRAK1 (Phospho-Thr387) antibody detects endogenous levels of IRAK1 only when phosphorylated at threonine 387.
ReferencesCao Z., Science 271:1128-1131(1996).
Reichwald K., Mamm. Genome 11:182-190(2000).