Other Names EC 2.7.11.10, I-kappa-B kinase 2, I-kappa-B-kinase beta, IKK-B, IKK-beta, IKK2, IKKB, IkBKB, NFKBIKB, Nuclear factor NF-kappa-B inhibitor kinase beta, kinase IKK-beta
All Sites Human: Tyr199; Mouse: Tyr199; Rat: Tyr199
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human IKK-β around the phosphorylation site of tyrosine 199 (Q-K-YP-T-V).
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity IKK-β (Phospho-Tyr199) antibody detects endogenous levels of IKK-β only when phosphorylated at tyrosine 199.
ReferencesZhi-Wei Li, J. Immunol., May 2003; 170: 4630.
Wen-Hui Hu, J. Biol. Chem., Aug 2005; 280: 29233 - 29241.
S. Escotte, Eur. Respir. J., Apr 2003; 21: 574 - 581.
Dirk Haller, J. Biol. Chem., Oct 2002; 277: 38168 - 38178.