Other Names ADRBK1, ARBK1, BARK, BARK1, Beta-ARK-1, Beta-adrenergic receptor kinase 1, EC 2.7.11.15, G protein receptor kinase 2, G- protein coupled receptor kinase 2, kinase GRK2
All Sites Human: Ser29; Mouse: Ser29; Rat: Ser29
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human GRK2 around the phosphorylation site of serine 29 (R-A-SP-K-K).
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity GRK2 (Phospho-Ser29) antibody detects endogenous levels of GRK2 only when phosphorylated at serine 29.
ReferencesAarti N. Desai, J. Pharmacol. Exp. Ther., Jun 2006; 317: 1027 - 1035.
John A. Gray, Mol. Pharmacol., Nov 2001; 60: 1020.
Anne Vroon, J. Leukoc. Biol., May 2004; 75: 901 - 909.
R. J. Hughes, Am J Physiol Cell Physiol, Mar 1996; 270: C885 - C891.