Other Names CD135, EC 2.7.10.1, FL cytokine receptor precursor, FLK-2, FLT-3, FLT3, Fetal liver kinase 2, STK-1, STK1, Stem cell tyrosine kinase 1, flk-2, kinase Flt3
All Sites Human: Tyr599; Mouse: Tyr600
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human FLT3 around the phosphorylation site of tyrosine 599 (Y-E-YP-D-L).
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity FLT3 (Phospho-Tyr599) antibody detects endogenous levels of FLT3 only when phosphorylated at tyrosine 599.
ReferencesSmall D., Proc. Natl. Acad. Sci. U.S.A. 91:459-463(1994).
Rosnet O., Blood 82:1110-1119(1993).
Greenman C., Nature 446:153-158(2007).
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells