Other Names EC 2.7.10.1, FGFBR, FGFR-1, FGR1, FLG, FLT2, Fms-like tyrosine kinase-2, MFR, bFGF-R, c-fgr, kinase FGFR1
All Sites Human: Tyr654; Mouse: Tyr654; Rat: Tyr561
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human FGFR1 around the phosphorylation site of tyrosine 654 (D-Y-YP-K-K).
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity FGFR1 (Phospho-Tyr654) antibody detects endogenous levels of FGFR1 only when phosphorylated at tyrosine 654.
ReferencesChitta S. Kasyapa, Blood, May 2006; 107: 3693 - 3699.
Benoit Rousseau, Cancer Res., Apr 2004; 64: 2490 - 2495.
Takayuki Nakayama, Blood, Feb 2007; 109: 1363 - 1372.