Other Names EC 2.7.10.1, FGFBR, FGFR-1, FGR1, FLG, FLT2, Fms-like tyrosine kinase-2, MFR, bFGF-R, c-fgr, kinase FGFR1
All Sites Human: Tyr766; Mouse: Tyr766; Rat: Tyr673
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human FGFR1 around the phosphorylation site of tyrosine 766 (Q-E-YP-L-D).
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity FGFR1 (Phospho-Tyr766) antibody detects endogenous levels of FGFR1 only when phosphorylated at tyrosine 766.
ReferencesChitta S. Kasyapa. Blood, May 2006; 107: 3693 - 3699.
Benoit Rousseau. Cancer Res., Apr 2004; 64: 2490 - 2495.
Takayuki Nakayama. Blood, Feb 2007; 109: 1363 - 1372.
Qing Wang. Development, Oct 2001; 128: 3867.
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells