Other Names CAD, CALD1, CDM, L-caldesmon, Non-muscle caldesmon
All Sites Human: Ser789; Mouse: Ser560; Rat: Ser534
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human Caldesmon around the phosphorylation site of serine 789 (V-T-SP-P-T).
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity Caldesmon (Phospho-Ser789) antibody detects endogenous levels of Caldesmon only when phosphorylated at serine 789.
ReferencesRobert Eves, J. Cell Sci., May 2006; 119: 1691 - 1702.
Shigeko Yamashiro, Mol. Biol. Cell, Jan 2001; 12: 239.
KS Warren, J. Cell Biol., Apr 1994; 125: 359.
Ping-Pin Zheng, Am. J. Pathol., Jun 2004; 164: 2217 - 2228.