Other Names A-SCID protein, ARTEMIS, ASCID, DCLRE1C, DCR1C, DNA cross-link repair 1C protein, EC 3.1.-.-, SCIDA, SNM1- like protein, SNM1C
All Sites Human: Ser516; Mouse: Ser518
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human Artemis around the phosphorylation site of serine 516 (G-G-SP-Q-S).
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity Artemis (Phospho-Ser516) antibody detects endogenous levels of Artemis only when phosphorylated at serine 516.
ReferencesMoshous D., Cell 105:177-186(2001).
Li L., J. Immunol. 168:6323-6329(2002).
Ota T., Nat. Genet. 36:40-45(2004).