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Primary Antibodies
IRS-1 (Phospho-Ser612) Antibody
$225/ 1mg/ml
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Other NamesIRS-1, IRS1, Insulin receptor substrate-1
All SitesHuman: Ser616; Mouse: Ser612; Rat: Ser612
Storage/StabilityStore at -20℃/1 year
Form Or Antibody
Form of AntibodyRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
ImmunogenThe antiserum was produced against synthesized phosphopeptide derived from human IRS-1 around the phosphorylation site of serine 612 (P-M-SP-P-G).
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/SensitivityIRS-1 (Phospho-Ser612) antibody detects endogenous levels of IRS-1 only when phosphorylated at serine 612.
ReferencesXJ Sun, J. Biol. Chem., Nov 1992; 267: 22662 - 22672.
Laurent Delahaye, Endocrinology, Dec 1998; 139: 4911.
Angela M. Valverde, Mol. Cell. Biol., Apr 2001; 21: 2269 - 2280.
Xiao Jian Sun, J. Biol. Chem., May 1996; 271: 10583.
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Laurent Delahaye, Endocrinology, Dec 1998; 139: 4911.
Angela M. Valverde, Mol. Cell. Biol., Apr 2001; 21: 2269 - 2280.
Xiao Jian Sun, J. Biol. Chem., May 1996; 271: 10583.
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Western blot analysis of extracts from HUVEC cells, treated with insulin (0.01U/ml, 30mins), using IRS-1 (Phospho-Ser612) antibody.
Conjugated Antibody
This product is also available conjugated. Format: E11-0447A-Conjugate. Price: $485 / Size: 100μl.
E11-0447A-FITC$485 / 100μlE11-0447A-Biotin$485 / 100μlE11-0447A-HRP$485 / 100μlE11-0447A-AP$485 / 100μlE11-0447A-AF350$485 / 100μlE11-0447A-AF405M$485 / 100μlE11-0447A-AF488$485 / 100μlE11-0447A-AF514$485 / 100μlE11-0447A-AF532$485 / 100μlE11-0447A-AF555$485 / 100μlE11-0447A-AF568$485 / 100μlE11-0447A-AF405S$485 / 100μlE11-0447A-AF405L$485 / 100μlE11-0447A-AF546$485 / 100μlE11-0447A-AF594$485 / 100μlE11-0447A-AF610$485 / 100μlE11-0447A-AF635$485 / 100μlE11-0447A-AF647$485 / 100μlE11-0447A-AF680$485 / 100μlE11-0447A-AF700$485 / 100μlE11-0447A-AF750$485 / 100μlE11-0447A-AF790$485 / 100μlE11-0447A-APC$485 / 100μlE11-0447A-PE$485 / 100μlE11-0447A-Cy3$485 / 100μlE11-0447A-Cy5$485 / 100μlE11-0447A-Cy5.5$485 / 100μlE11-0447A-Cy7$485 / 100μlE11-0447A-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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