All Names
AlternameInterleukin-3 receptor alpha chain, IL-3R-alpha, CD123 antigen, IL3RA
All SitesHuman: Tyr593; Mouse: Tyr595
Form Or Antibody
Form of AntibodyRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/StabilityStore at -20℃/1 year
ImmunogenThe antiserum was produced against synthesized phosphopeptide derived from human IL3R around the phosphorylation site of tyrosine 593 (G-P-YP-L-G).
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/SensitivityIL3R (Phospho-Tyr593) antibody detects endogenous levels of IL3R only when phosphorylated at tyrosine 593.
ReferencesMichelle M. Le Beau, Blood, Aug 2003; 102: 1072 - 1074.
Elena Cattaneo, J. Biol. Chem., Sep 1996; 271: 23374.
Patricia McLoughlin, J. Biol. Chem., Sep 2002; 277: 37045 - 37053.
Louise Edvardsson, Blood, Nov 2004; 104: 4120.
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells