All Names
AlternameFAS-associating death domain-containing protein, MORT1, Mediator of receptor induced toxicity
Form Or Antibody
Form of AntibodyRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/StabilityStore at -20℃/1 year
ImmunogenThe antiserum was produced against synthesized phosphopeptide derived from human FADD around the phosphorylation site of serine 194 (A-M-SP-P-M).
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/SensitivityFADD (Phospho-Ser194) antibody detects endogenous levels of FADD only when phosphorylated at serine 194.
ReferencesWen-Chen Yeh, Science, Mar 1998; 279: 1954.
Carsten Scaffidi, J. Immunol., Feb 2000; 164: 1236.
Anna A. Kuang, J. Biol. Chem., Aug 2000; 275: 25065.
Guoan Chen, PNAS, Aug 2005; 102: 12507 - 12512.