All Names
AlternameB-dynamin, D100, DNM, DNM1, Dynamin BREDNM19, Dynamin, brain, EC 3.6.5.5, dynamin-1
All SitesHuman: Ser774; Mouse: Ser770; Rat: Ser774
Form Or Antibody
Form of AntibodyRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/StabilityStore at -20℃/1 year
ImmunogenThe antiserum was produced against synthesized phosphopeptide derived from human DYN1 around the phosphorylation site of serine 774 (R-R-SP-P-T).
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/SensitivityDynamin-1 (Phospho-Ser774) antibody detects endogenous levels of DYN1 only when phosphorylated at serine 774.
ReferencesR. Martin, Eukaryot. Cell, Dec 2004; 3: 1574 - 1588.
D Eshel, PNAS, Dec 1993; 90: 11172.
Yoram Altschuler, J. Cell Biol., Dec 1998; 143: 1871.
Byeong Doo Song, Mol. Biol. Cell, May 2004; 15: 2243 - 2252.
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells