Other Names C-SRC kinase, CSK, CYL, EC 2.7.10.2, MPK-2, kinase CSK
All Sites Human: Ser364; Mouse: Ser364; Rat: Ser364
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human Csk around the phosphorylation site of serine 364 (K-F-SP-T-K).
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity Csk (Phospho-Ser364) antibody detects endogenous levels of Csk only when phosphorylated at serine 364.
ReferencesYoshiharu Takayama, J. Biol. Chem., Jan 1999; 274: 2291.
Bing Wang, Mol. Cell. Biol., Feb 2001; 21: 1077 - 1088.
Deirdre McGarrigle, J. Biol. Chem., Apr 2006; 281: 10583 - 10588.
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells