All Names
AlternameACAC, ACACA, ACC-alpha, ACCA, Acetyl-CoA carboxylase 1, EC 6.3.4.14, EC 6.4.1.2
All SitesHuman: Ser80; Mouse: Ser79; Rat: Ser79
Form Or Antibody
Form of AntibodyRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/StabilityStore at -20℃/1 year
ImmunogenThe antiserum was produced against synthesized phosphopeptide derived from human ACC1 around the phosphorylation site of serine 79 (S-M-SP-G-L).
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/SensitivityACC1 (Phospho-Ser80) antibody detects endogenous levels of ACC1 only when phosphorylated at serine 79.
ReferencesNaomoto Harada, Mol. Cell. Biol., Mar 2007; 27: 1881 - 1888.
Naomoto Harada, Mol. Cell. Biol., May 2007; 27: 3556.
D. A. Somers, Plant Physiology, Mar 1993; 101: 1097.
M. Joachimiak, PNAS, Sep 1997; 94: 9990.
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells