Other Names ABL1, EC 2.7.1.112, JTK7, Proto-oncogene tyrosine-protein kinase ABL1, c-ABL, p150
All Sites Human: Tyr204; Mouse: Tyr204; Rat: Tyr204
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human Abl around the phosphorylation site of tyrosine 204 (K-L-YP-V-S).
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity Abl (Phospho-Tyr204) antibody detects endogenous levels of Abl only when phosphorylated at tyrosine 204.
ReferencesThomas Burmeister, Blood, Nov 2006; 108: 3556 - 3559.
Kim De Keersmaecker, Blood, Jun 2005; 105: 4849 - 4852.
Florian Klein, J. Exp. Med., Mar 2004; 199: 673.
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells