All Names
AlternameABL1, EC 2.7.1.112, JTK7, Proto-oncogene tyrosine-protein kinase ABL1, c-ABL, p150
All SitesHuman: Tyr412; Mouse: Tyr412; Rat: Tyr412
Form Or Antibody
Form of AntibodyRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/StabilityStore at -20℃/1 year
ImmunogenThe antiserum was produced against synthesized phosphopeptide derived from human Abl1 around the phosphorylation site of tyrosine 412 (D-T-YP-T-A).
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/SensitivityAbl (Phospho-Tyr412) Antibody detects endogenous levels of Abl1 only when phosphorylated at tyrosine 412.
ReferencesFotis A. Asimakopoulos, Blood, Oct 1999; 94: 2452 - 2460.
Thomas Burmeister, Blood, Nov 2006; 108: 3556 - 3559.
Kim De Keersmaecker, Blood, Jun 2005; 105: 4849 - 4852.
Florian Klein, J. Exp. Med., Mar 2004; 199: 673.